Very good question youmin.moon! You've already identified some key issues in both (A) and (D), excellent work! Let's break down the question completely.
When approaching a Synthesis question, we need to be prepared to deploy the full complement of reading comprehension skills: identification, inference, and synthesis.
The passage is focused primarily on characteristics the current reduction of biological diversity: it's a very bad thing and we humans are causing it. This appears to match up quite nicely with
(E). We can support each element of this answer with line references:
"human-induced" - lines 3-4 "as human populations expand", lines 33-34 "human activity has had a devastating effect"
"incalculable proportions" - lines 7-8 "beyond calculation", line 45-46 "consequences are also the least predictable"
"potentially grave consequences" - line 8 "certain to be harmful", lines 52-53 "serious strategic error...will be increasingly regretted"
Not the Point!(A) Unsupported/Contradicted. It may be a setback for science/society, but the passage doesn't use that language. Additionally, biodiversity reductions are actually not at all 'irreversible'. The passage indicates that our planet's general biodiversity picture has bounced back multiple times following mass extinctions, albeit slowly.
(B) Narrow Scope. The relationship between "biological wealth" and "material/cultural wealth" is a small detail in this passage. Also, this relationship is raised to support the point that bio-wealth is unstudied, unappreciated, and taken for granted. The author never claims which form of 'wealth' is more significant than the other.
(C) Unsupported. While the passage mentions both the enormous diversity of life and the past mass extinctions, it does not suggest the former
required the latter. In fact, the high diversity was achieved
in spite of the mass extinctions.
(D) Unsupported. We humans are reducing biodiversity, but does that mean we are "initiating a mass extinction"? And even if we were, is the passage predicting that ours will outstrip other mass extinction episodes? That's a tall order. There are no predictions in the passage about just how our biodiversity reductions will compare in the end.
Please let me know if this completely answers your question!